My project focuses on advancing CAR-T cell therapy using microfluidic technologies in collaboration with Dr. Tobias Weiss at the University Hospital Zurich. First, I am using microfluidic mechanoporation to transfect mRNA into peripheral blood mononuclear cells (PBMCs), enabling assessment of transfection efficiency and its impact on CAR-T cell functionality. Second, I aim to sort cells with high exosome secretion through droplet-based microfluidic sorting, evaluating their potential to enhance the therapeutic efficacy of CAR-T cells.